What is the best bit or end mill to use when cutting Acrylic, and what are the best speeds and feeds?

Acrylic is a very common material to cut on a CNC.  It can be used for anything from making windows in projects to making edge-lit LED signs.  Acrylic can be a tricky material to cut successfully, mainly because many people will run the RPM of the cutter too fast with a feed rate that is too slow, thus causing melting of the plastic.   The trick is to get nice clean chips as you cut.

The following article goes into this in detail:  Cutting Acrylic – 8 Guidelines To Getting The Best Results