What software do I need to run the 4th Axis system?

In order to use the 4th Axis, you need to have a CAM program that will support creation of the tool path for the 4th axis.  Two possible solutions include:

Vectric VCarve Pro (the Desktop version does not support 4th axis).  VCarve Pro has a Gadget that will allow you to take a 2D design and wrap it around a cylinder to create a round object.  The following video shows you how:

The other option is to use Deskproto Multi-axis addition.  This software will also allow you to create a 4th axis job.  An added benefit of this program is that it allows you to take a solid 3D model (stl, obj) and place inside a workpiece and then you can carve that object out.  See video below showing a Homer Simpson being cut out of foam.